Definition

Inflammation of the upper airways, the larynx, trachea and bronchi.

Aetiology

  • Viral: parainfluenza influenza virus, respiratory syncytial virus (RSV), adenovirus and measles. 

  • Bacteria (rare): bordetella pertussis (whooping cough).

  • Fungal (very rare).

Pathophysiology

  1. Inflammation of upper airway mainly larynx, trachea and bronchi caused mainly by invasion of viruses. 

  2. Immune response causes inflammation and mucus production. 

  3. Swelling and narrowing of airways which causes symptoms of barking cough, stridor and shortness of breath.

Risk factors

  • Age: common in children under the age of 5. Peak around the age of 6 months to 3 years old. 

  • Exposure to infected individuals. 

  • Background of asthma, allergies or other respiratory conditions. 

  • Family history.

  • Weak immune system: those with chronic conditions such as diabetes, COPD, asthma, HIV/AIDs etc.

  • Smoking, air pollution and other environmental causes.

Sign and symptoms

  • Barking cough

  • Stridor 

  • Hoarseness 

  • In children you may observe symptoms of respiratory distress: tracheal tug,  Intercostal recession and cyanosis

Diagnosis and investigations

  • Physical examination: general exam e.g. cardio, respiratory, GI examination, pulse oximetry, respiratory rate and capillary refil. 

  • Chest X-ray not generally used because it can make a child more distressed. 

  • Oxygen saturation measurement: if low O2 (<95%) child must be admitted.

Management

  • Steroids oral dexamethasone (0.15 mg/kg) and advice parents if stridor continues to go to hospital. 

  • Example, Dexamethasone 2mg/5ml - 5 ml once only and stop 75ml.

  • Hospital admission: nebuliser or oxygen therapy might be commenced.

 
 
 

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